In this Section
 
WP logo two line
Search Icon
Search Arrow
 

Faculty and Staff

David Snyder

Professor • Department of Chemistry

Professional Interests

My research lies at the intersection of computational and experimental biochemistry. In particular, I am interested in developing -- and exploring the mathematics underlying -- processing techniques (e.g. covariance NMR) that facilitate the use of NMR in exploring the chemistry of complex mixtures. I am also interested in the evolution of protein flexibility and of "moonlighting" proteins (and the implications of each in aging and disease processes as well as in protein engineering) as well as in the use of computational and spectroscopic techniques to identify protein ligands, in particular allosteric modulators of protein/small molecule and protein/protein interactions. My research also explores the applications of such techniques to fragment-based drug design.

My Google Scholar page is https://scholar.google.com/citations?user=_Y2QjMgAAAAJ&hl=en&oi=sra and my ORCID page is https://orcid.org/0000-0001-6608-2975

I do most of my programming nowadays in MATLAB. My MATLAB central file exchange page is https://www.mathworks.com/matlabcentral/profile/authors/1420896 .

Other Interests

Music (composition and performance), Photography (see my DeviantArt page at https://www.deviantart.com/davidasnyder/gallery for some of my photography, including of the visually inspiring WPUNJ campus).

Degrees

PhD Biochemistry, Rutgers New Brunswick, NJ

BS Biology; Mathematics, UC Irvine Irvine, CA

Specialization

Computational Biochemistry, Nuclear Magnetic Resonance

Representative Publications


Application of CoLD-CoP to Detecting Competitively and Cooperatively Binding Ligands; Biomolecules; Volume 14, 2024


Patterns in Protein Flexibility: A Comparison of NMR “Ensembles”, MD Trajectories, and Crystallographic B-Factors; Molecules; Volume 26, Issue Special Issue: "The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder" 2021


On bounding the Thompson metric by Schatten norms; , Cogent Mathematics & Statistics; 2019


Prediction of protein flexibility using a conformationally restrained contact map; , Proteins: Structure, Function and Bioinformatics; Volume 86, Issue 10 2018


The expanded FindCore method for identification of a core atom set for assessment of protein structure prediction; , Proteins: Structure, Function, and Bioinformatics; Volume 82, Issue S2 2014

Representative Presentations


Tyrosinase enhancement of amino acid catalyzed aldol condensation
ACS Fall 2024 Meeting and Exposition American Chemical Society
, 2024


Docking studies on tyrosinase and SARS-CoV2 nsp16: Discovery of novel enzymatic activities and drug repurposing
ACS Spring 2021 National Meeting and Exposition American Chemical Society
, 2021


Current Perspectives in Covariance NMR
IVAN Research Round-table Workshop MR Resources
, 2020

Notable Courses Taught

Biochemistry I (CHEM 4270)
Biochemistry II (CHEM 4280)
Chemistry for Health Sciences (CHEM 1330)
Theoretical and Physical Methods (CHEM 6004)

4060 Hennings Science East

By appointment

Request Info Visit Apply


300 Pompton Road | Wayne, New Jersey 07470
(973) 720-2000

Copyright © 2024 | Privacy Policy